Linked Life Data

3878392

Source:http://linkedlifedata.com/resource/pubmed/id/3878392

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-1-29
pubmed:abstractText
Lack of toxicity of polyadenylic-polyuridylic acid [poly(A).poly(U)] in rodents is demonstrated. This immunomodulator has antitumor activity when used as an adjuvant to surgery or to chemotherapy. Biological mediator properties that shed some light on the mechanism of tumor inhibition are the potentiating effects of poly(A).poly(U) on T cells, natural killer cells, and interferon activity as indicated by the level of the enzyme 2-5 A synthetase. In vivo organ distribution and pharmacokinetic studies in rabbits by a scintigraphic technique, subcellular fractionation, and sucrose sedimentation profiles indicate a surprising metabolic stability (measured in days).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0732-6580
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
490-4
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Polyadenylic-polyuridylic acid: biological response-modifying activities in mice. In vivo organ distribution and pharmacokinetics in rabbits.
pubmed:publicationType
Journal Article