Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-5-15
pubmed:abstractText
Aspergillus fumigatus keratitis was established in rabbits by intrastromal injection of a suspension containing 5,000 spores. After a 48-hour incubation period, the animals were treated with oral and topical ketoconazole alone and in combination with topical natamycin for five days. Colony counts per cornea were obtained at the conclusion of the treatment period. Based on these colony counts, neither oral nor topical ketoconazole was effective despite moderate in vitro sensitivity of the fungus to ketoconazole. Oral and topical ketoconazole used in conjunction with natamycin, however, appeared to augment sterilization of A. fumigatus in this model of fungal keratitis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0002-9394
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
476-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Treatment of Aspergillus fumigatus keratitis in rabbits with oral and topical ketoconazole.
pubmed:publicationType
Journal Article, Comparative Study