Linked Life Data

3860929

Source:http://linkedlifedata.com/resource/pubmed/id/3860929

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1985-9-11
pubmed:abstractText
The luminal gastric mucosa of anesthetised rats was uniformly exposed to 70% ethanol for 30-45 seconds. Ninety-six per cent of the superficial epithelium was immediately destroyed. The mucosa was allowed to heal for 60 minutes, during which time 85% of the superficial mucosa had re-epithelialised. A thick gelatinous layer of necrotic cells and mucosal exudate formed over the restituted epithelium. To determine whether the mucosa could withstand a second ethanol insult, the same stomachs were re-exposed to 70% ethanol for 30-45 seconds and fixed for quantitative light microscopy. Significant damage to the newly formed epithelium was observed only when the gelatinous layer was first removed and then followed by a second ethanol insult. This resulted in uniform superficial damage to 92% of the mucosal surface with accompanying vascular stasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0085-5928
pubmed:author
pubmed:issnType
Print
pubmed:volume
110
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-72
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Gastric mucosal resistance to a repeated ethanol insult.
pubmed:publicationType
Journal Article