Linked Life Data

386063

Source:http://linkedlifedata.com/resource/pubmed/id/386063

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1979-12-29
pubmed:abstractText
Twenty-two adult patients with active endoscopically proven reflux oesophagitis entered a double-blind trial of treatment with either cimetidine (1 g/day) or placebo. A repeat endoscopy was carried out at eight weeks after the beginning of treatment on 19 of the patients. The mucosa appeared macroscopically normal at eight weeks in 81.8% of the cimetidine-treated patients, while 90% of patients were described histologically as having a normal or unremarkable mucosa. The results in placebo-treated patients were 55.6% and 44.4% respectively. The cimetidine-treated patients consumed significantly less antacids than the placebo-treated patients, and the over all assessment of their well-being was significantly better (90.9% patient satisfaction with treatment in the cimetidine group compared to 18.2% in the placebo group). Two patients in the placebo group did not complete the trial due to continuing severity of their symptoms, while none in the cimetidine group felt that their condition had remained static or was worse.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0025-729X
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Cimetidine in the treatment of reflux oesophagitis.
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial