Linked Life Data

3828578

Source:http://linkedlifedata.com/resource/pubmed/id/3828578

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-4-28
pubmed:abstractText
Reflex arterial pressure regulation was studied in control and sodium-depleted rats fed a diet containing 0.1 mEq Na+ for 6 days associated with furosemide (5 mg/kg, ip, on the 1st and 5th day). The hypertensive response produced in conscious rats by bilateral common carotid occlusion (5 to 60 s) was significantly smaller in the sodium-depleted rats (MAP = 113 +/- 3 mmHg) than in the controls (MAP = 121 +/- 2 mmHg) in terms of absolute as well as relative values. Sixty min after recovery from ether anesthesia, the rats submitted to sino-aortic denervation showed a similar relative increase in MAP (30%), whereas the hypertensive level attained by the sodium-depleted rats was only mild (MAP = 126 +/- 5 mmHg). Sodium-depleted rats required 3.5 and 2.4 times larger dose of norepinephrine and angiotensin II, respectively, than the control rats to produce an increase in MAP of 20-25 mmHg. Changes in vascular reactivity associated with impaired cardiac function might be important factors to explain the decreased pressor responses produced by carotid occlusion and by sino-aortic denervation in sodium-depleted rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0100-879X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
319-25
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Cardiovascular reflexes in conscious sodium-depleted rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't