| pubmed-article:3804026 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0019169 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0019721 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0000189 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C1446409 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0870432 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C1705417 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C1555465 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:3804026 | lifeskim:mentions | umls-concept:C0205191 | lld:lifeskim |
| pubmed-article:3804026 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:3804026 | pubmed:dateCreated | 1987-3-18 | lld:pubmed |
| pubmed-article:3804026 | pubmed:abstractText | In this study we have examined the density of HLA class I protein display on the hepatocytes of patients with HBe antigen (HBeAg) or anti-HBe (HBeAb) positive chronic hepatitis B virus (HBV) infection and related this to the level of interferon activation of these cells determined by measuring hepatic oligo 2-5A synthetase activity. In HBeAg positive patients the density of HLA class I (HLA-I) protein was not significantly increased above that found in uninfected liver, but levels of 2-5A synthetase were twice normal. In anti-HBe positive patients, HLA-I density was markedly increased in the presence of normal 2-5A synthetase activity. These data are consistent with type I (alpha or beta) interferon activation of the hepatocytes in HBeAg positive patients and type II (gamma) interferon activity in anti-HBe positive subjects. | lld:pubmed |
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| pubmed-article:3804026 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3804026 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3804026 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3804026 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3804026 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3804026 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:3804026 | pubmed:issn | 0017-5749 | lld:pubmed |
| pubmed-article:3804026 | pubmed:author | pubmed-author:ThomasH CHC | lld:pubmed |
| pubmed-article:3804026 | pubmed:author | pubmed-author:IkedaTT | lld:pubmed |
| pubmed-article:3804026 | pubmed:author | pubmed-author:PignatelliMM | lld:pubmed |
| pubmed-article:3804026 | pubmed:author | pubmed-author:LeverA MAM | lld:pubmed |
| pubmed-article:3804026 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3804026 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:3804026 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3804026 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3804026 | pubmed:pagination | 1498-501 | lld:pubmed |
| pubmed-article:3804026 | pubmed:dateRevised | 2010-9-13 | lld:pubmed |
| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
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| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
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| pubmed-article:3804026 | pubmed:meshHeading | pubmed-meshheading:3804026-... | lld:pubmed |
| pubmed-article:3804026 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3804026 | pubmed:articleTitle | Relationship of HLA protein display to activation of 2-5A synthetase in HBe antigen or anti-HBe positive chronic HBV infection. | lld:pubmed |
| pubmed-article:3804026 | pubmed:publicationType | Journal Article | lld:pubmed |
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