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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0004927,
umls-concept:C0028633,
umls-concept:C0034693,
umls-concept:C0443199,
umls-concept:C0871261,
umls-concept:C1512035,
umls-concept:C1515655,
umls-concept:C1555903,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1880497,
umls-concept:C1996904,
umls-concept:C2603343,
umls-concept:C2911692
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pubmed:issue |
2
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pubmed:dateCreated |
1987-3-18
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pubmed:abstractText |
The reactivity of dopaminergic (DA) terminals in the nucleus accumbens was investigated in male rats submitted to tail-pinch or various social interactions. The DA activity was assessed by measurement of the presynaptic metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) by using differential pulse voltammetry in free moving preparations. Tail-pinch lasting 5 min or 10 min was followed by increases in DA activity of 25% and 35%, respectively. Three types of social interaction were used: interaction with an aggressive male congener, interaction with a non-aggressive male congener or interaction with a female congener. The greatest increase in dopaminergic activity (40%) was observed after the aggressive interaction. The reactivity of the DA neurons within the nucleus accumbens is, therefore, dependent on the characteristics of the behavioral situation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
397
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-400
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3801880-3,4-Dihydroxyphenylacetic Acid,
pubmed-meshheading:3801880-Afferent Pathways,
pubmed-meshheading:3801880-Animals,
pubmed-meshheading:3801880-Behavior, Animal,
pubmed-meshheading:3801880-Dopamine,
pubmed-meshheading:3801880-Electrochemistry,
pubmed-meshheading:3801880-Female,
pubmed-meshheading:3801880-Male,
pubmed-meshheading:3801880-Neurons, Afferent,
pubmed-meshheading:3801880-Nucleus Accumbens,
pubmed-meshheading:3801880-Pain,
pubmed-meshheading:3801880-Rats,
pubmed-meshheading:3801880-Rats, Inbred Strains,
pubmed-meshheading:3801880-Septal Nuclei,
pubmed-meshheading:3801880-Social Behavior
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pubmed:year |
1986
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pubmed:articleTitle |
Differential reactivity of dopaminergic neurons in the nucleus accumbens in response to different behavioral situations. An in vivo voltammetric study in free moving rats.
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pubmed:publicationType |
Journal Article
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