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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1987-2-19
|
| pubmed:abstractText |
To investigate the effect of topical cyclosporin A (CSA) on the rabbit cornea, both eyes of 80 animals were treated with CSA 2% eye drops over a 3-week period under various conditions. CSA was dissolved in castor oil or ethanol 13.8 vol. %. Slit-lamp, scanning and transmission electron microscopic examinations were performed. CSA 2% in castor oil given 5 times daily showed no damage to either the corneal epithelium or endothelium. In contrast the solutions containing ethanol revealed considerable epithelial cell damage.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0721-832X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
224
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
520-4
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:3792847-Animals,
pubmed-meshheading:3792847-Castor Oil,
pubmed-meshheading:3792847-Cornea,
pubmed-meshheading:3792847-Cyclosporins,
pubmed-meshheading:3792847-Ethanol,
pubmed-meshheading:3792847-Male,
pubmed-meshheading:3792847-Microscopy, Electron,
pubmed-meshheading:3792847-Microscopy, Electron, Scanning,
pubmed-meshheading:3792847-Rabbits,
pubmed-meshheading:3792847-Solvents,
pubmed-meshheading:3792847-Wound Healing,
pubmed-meshheading:3792847-Wounds, Nonpenetrating
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
The effect of topical cyclosporin A on the rabbit cornea. A clinical and electron microscopic study.
|
| pubmed:publicationType |
Journal Article
|