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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-2-19
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pubmed:abstractText |
Use of oral neomycin as a hypocholesterolemic agent was found to decrease plasma alpha tocopherol levels during a 9-month, randomized, crossover placebo-controlled clinical trial with controlled diet. Pooled data from each treatment sequence showed a placebo alpha-tocopherol level of 1,896 +/- 643 micrograms/dl, and a neomycin alpha-tocopherol concentration of 1,449 +/- 451 micrograms/dl (p less than .01). When all subjects were on neomycin simultaneously, the level increased to 1,665 +/- 614 micrograms/dl (p less than .05 from placebo). Normal plasma alpha-tocopherol ranges from 400-1,000 micrograms/dl. Neomycin treatment reduces but does not normalize elevated levels of alpha-tocopherol found in Type II hyperlipoproteinemia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0272-3530
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
325-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3792214-Cholesterol, LDL,
pubmed-meshheading:3792214-Diet,
pubmed-meshheading:3792214-Female,
pubmed-meshheading:3792214-Humans,
pubmed-meshheading:3792214-Hyperlipoproteinemia Type II,
pubmed-meshheading:3792214-Lipids,
pubmed-meshheading:3792214-Male,
pubmed-meshheading:3792214-Neomycin,
pubmed-meshheading:3792214-Vitamin E
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pubmed:year |
1986
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pubmed:articleTitle |
The effect of neomycin on plasma alpha tocopherol levels in type II hyperlipoproteinemia.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|