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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-12-17
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pubmed:abstractText |
The influence of delta-sleep inducing peptide (DSIP) on rat pineal N-acetyltransferase (NAT) activity and melatonin levels was examined. Young adult rats received an injection of either saline or DSIP (either 15, 30 or 60 nmol/kg) at 20:00 h, immediately before lights out. DSIP at a dose of 15 nmol/kg significantly retarded the nighttime rise of pineal NAT activity and melatonin levels at 3 h into the dark phase. At the other two nocturnal time points (01:00 and 03:00 h) and the following morning (08:00 h) pineal NAT activity and melatonin levels were similar in all groups. The results confirmed a short-lived, dose-specific effect of DSIP on serotonin metabolism in the rat pineal gland.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3774211-Animals,
pubmed-meshheading:3774211-Arylamine N-Acetyltransferase,
pubmed-meshheading:3774211-Delta Sleep-Inducing Peptide,
pubmed-meshheading:3774211-Light,
pubmed-meshheading:3774211-Male,
pubmed-meshheading:3774211-Melatonin,
pubmed-meshheading:3774211-Pineal Gland,
pubmed-meshheading:3774211-Rats,
pubmed-meshheading:3774211-Serotonin,
pubmed-meshheading:3774211-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Influence of delta-sleep inducing peptide on melatonin synthesis in the rat pineal gland.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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