Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-11-19
pubmed:abstractText
In vitro tests with the urease inhibitor flurofamide demonstrated that the final inhibitory concentration of 0.5-4 microM on the growth of nine ureaplasma strains was largely ureaplasmastatic, requiring prolonged incubation to have a ureaplasmacidal effect. Intramuscular injection of flurofamide successfully eliminated genital infections of ureaplasma in sheep only when the treatment was repeated on two consecutive days. A dose rate of 5-20 mg/kg body weight eliminated the organism from naturally infected sheep, but 15-25 mg/kg body weight was required to eliminate the infection from eleven of fourteen experimentally, newly infected sheep. Administration of the flurofamide orally in the drinking water failed to eliminate ureaplasmas from any of twenty newly infected sheep.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0140-7783
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
280-5
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Investigation into the inhibitory effect of flurofamide on animal ureaplasmas and its use in the treatment of ureaplasma-infected sheep.
pubmed:publicationType
Journal Article