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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-11-7
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pubmed:abstractText |
The development of glutathione S-transferase and glutathione peroxidase activities has been studied in human lung cytosols. Whilst no clear change in glutathione peroxidase activity was identified, expression of the acidic glutathione S-transferase isoenzyme decreased markedly after 15 weeks of gestation so that at birth the level of activity of this isoenzyme was only about 20% of that in samples obtained during the first trimester. Basic glutathione S-transferase isoenzymes were weakly expressed during development and usually comprised less than 10% of cytosolic activity. Ion-exchange studies identified several basic isoenzymes that may correspond to the alpha, beta, gamma, delta and epsilon set previously identified in liver. Weak expression of apparently near-neutral isoenzymes was also detected; they were detected in only a few cytosols.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
883
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
448-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3756211-Chromatography, Ion Exchange,
pubmed-meshheading:3756211-Cytosol,
pubmed-meshheading:3756211-Gestational Age,
pubmed-meshheading:3756211-Glutathione Peroxidase,
pubmed-meshheading:3756211-Glutathione Transferase,
pubmed-meshheading:3756211-Humans,
pubmed-meshheading:3756211-Infant,
pubmed-meshheading:3756211-Infant, Newborn,
pubmed-meshheading:3756211-Isoelectric Focusing,
pubmed-meshheading:3756211-Lung
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pubmed:year |
1986
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pubmed:articleTitle |
The development of glutathione S-transferase and glutathione peroxidase activities in human lung.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|