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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1986-8-20
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pubmed:abstractText |
The effect of moderate hypoxemia upon postural sympathetic vasoconstrictor reflexes in skeletal muscle was studied in five healthy young students, aged 20-30 years. The vasoconstrictor response to head-up tilt was studied in brachio radial muscle kept at heart level and in the anterior tibial muscle. The local sympathetic veno-arteriolar axon reflex was studied in the anterior tibial muscle placed at heart level and lowered 30-50 cm below heart level. Muscle blood flow was measured by the local 133Xe wash-out technique. The measurements were carried out with the subject breathing atmospheric air and with the subject breathing 10-11% oxygen. No sign of orthostatic intolerance was seen during hypoxaemia as arterial blood pressure remained constant in the tilted position. Hypoxaemia did not alter the head-up tilt induced vasoconstriction in brachio-radial and anterior tibial muscles. The vasoconstriction elicited by the local veno-arteriolar reflex was slightly reduced during hypoxaemia. The results suggest that central orthostatic vasoconstrictor reflexes to muscle are essentially normal during moderate hypoxaemia, but local veno-arteriolar reflexes are slightly attenuated. This does not, however, significantly alter blood pressure control during head-up tilt.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0001-6772
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3728050-Adult,
pubmed-meshheading:3728050-Anoxia,
pubmed-meshheading:3728050-Axons,
pubmed-meshheading:3728050-Blood Pressure,
pubmed-meshheading:3728050-Humans,
pubmed-meshheading:3728050-Muscles,
pubmed-meshheading:3728050-Posture,
pubmed-meshheading:3728050-Reflex,
pubmed-meshheading:3728050-Sympathetic Nervous System,
pubmed-meshheading:3728050-Vascular Resistance,
pubmed-meshheading:3728050-Vasoconstriction
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pubmed:year |
1986
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pubmed:articleTitle |
Lack of effect of moderate hypoxaemia on human postural reflexes to skeletal muscle.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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