Linked Life Data

3706575

Source:http://linkedlifedata.com/resource/pubmed/id/3706575

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 2
pubmed:dateCreated
1986-6-16
pubmed:abstractText
The coupling patterns between the rhythm of a mechanical ventilator and the rhythm of spontaneous breathing were studied in enflurane-anesthetized adult human subjects. The spontaneous breathing pattern was altered in response to different frequencies and amplitudes of forced lung inflations. A 1:1 phase locking (the frequency of the mechanical ventilator is matched by the frequency of spontaneous breathing with a fixed phase between the 2 rhythms) was observed in a range of up to +/- 40% of some of the subject's spontaneous breathing frequencies. During 1:1 phase locking, there were marked changes in the expiratory duration as measured from the electromyogram of the diaphragm. The phase relationship between onset of inflation and onset of inspiration depended on the frequency and amplitude of mechanical inflation. At ventilator settings that did not give 1:1 phase locking, other simple phase-locked patterns, such as 1:2 and 2:1, or irregular non-phase-locked patterns were observed. Reflexes arising from lung inflation, which may underlie the entrainment, are discussed in the context of these results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
250
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R902-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Respiratory phase locking during mechanical ventilation in anesthetized human subjects.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't