Linked Life Data

3701052

Source:http://linkedlifedata.com/resource/pubmed/id/3701052

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1986-5-30
pubmed:abstractText
Female albino rats were exposed to carbon monoxide in concentrations ranging from 130 to 1030 mg/m3 for a period of 40 minutes. During the last 20 minutes of exposure, the rats were subject to forced run on a flat treadmill moving at a rate of 400 m/hour. Immediately after termination of exposure, the concentration of carboxyhemoglobin and lactic acid in blood, as also the concentration of carboxymyoglobin in the heart and skeletal muscles were determined. Work load did not influence the level of carboxyhemoglobin in blood, though inducing an increase in the concentration of carboxymyoglobin in both the heart muscle and the skeletal muscle. The increase in the concentration of lactic acid in the blood was observed only in rats exposed to carbon monoxide in an average concentration of 1030 mg/m3 and simultaneous work load. Results of the observations demonstrate that simultaneous effect of carbon monoxide and work load can induce more severe tissue hypoxia than could be expected on the basis of carboxyhemoglobin concentration in the blood.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0022-1732
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-62
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Effect of work load on the content of carboxymyoglobin in the heart and skeletal muscles of rats exposed to carbon monoxide.
pubmed:publicationType
Journal Article