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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1988-2-8
|
pubmed:abstractText |
In slices of parietal neocortex, evidence was obtained for the existence of a low-threshold Ca2+ conductance in most neurons. This conductance became apparent when resting membrane potential was held below -60 mV by continuously injected, depolarizing current. Under these conditions, brief hyperpolarizing pulses were followed by generation of tetrodotoxin (TTX)-resistant, Mn2+-sensitive, low-threshold spikes. The results suggest that in neocortex, as in many subcortical structures, low-threshold Ca current may be responsible for burst generation in some neurons.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
81
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
117-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3696461-Animals,
pubmed-meshheading:3696461-Calcium,
pubmed-meshheading:3696461-Guinea Pigs,
pubmed-meshheading:3696461-Manganese,
pubmed-meshheading:3696461-Membrane Potentials,
pubmed-meshheading:3696461-Neural Conduction,
pubmed-meshheading:3696461-Neurons,
pubmed-meshheading:3696461-Parietal Lobe,
pubmed-meshheading:3696461-Tetrodotoxin
|
pubmed:year |
1987
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pubmed:articleTitle |
Low-threshold calcium electrogenesis in neocortical neurons.
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pubmed:affiliation |
Corob Center for Medical Research, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|