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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1987-12-28
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pubmed:databankReference |
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pubmed:abstractText |
We purified a fragment of mouse DNA to which the large T protein of polyoma virus was bound in chromatin prepared from transformed mouse cells. This sequence, which is not repeated to a measurable extent within the mouse genome, does not show any significant homology to the viral ori region, except in a short region, which comprises a sequence related to the consensus for recognition by large T proteins ((A,T)GPuGGC). This region of pCG4 was confirmed by in vitro binding assays to be essential for T antigen binding.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1053-62
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3689383-Animals,
pubmed-meshheading:3689383-Antigens, Viral, Tumor,
pubmed-meshheading:3689383-Base Sequence,
pubmed-meshheading:3689383-Cell Transformation, Viral,
pubmed-meshheading:3689383-Chromatin,
pubmed-meshheading:3689383-Cloning, Molecular,
pubmed-meshheading:3689383-DNA,
pubmed-meshheading:3689383-DNA-Binding Proteins,
pubmed-meshheading:3689383-Mice,
pubmed-meshheading:3689383-Molecular Sequence Data,
pubmed-meshheading:3689383-Nucleoproteins,
pubmed-meshheading:3689383-Regulatory Sequences, Nucleic Acid
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pubmed:year |
1987
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pubmed:articleTitle |
High affinity binding of the large T protein of polyoma virus to a genomic mouse DNA sequence.
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pubmed:affiliation |
Unité 273 de l'INSERM, Université de Nice, France.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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