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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1987-12-23
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pubmed:abstractText |
A new human erythrocyte glycoprotein has been identified by immunoblotting with murine monoclonal antibodies under non-reducing conditions. The glycoprotein has a MW of 70,000 and carries Cromer-related blood group antigens. The monoclonal antibodies also react with normal peripheral blood leucocytes and platelets and several haemopoietic cell lines. The glycoprotein has a reduced MW after sialidase treatment. The MW is markedly reduced in Tn erythrocyte membranes and slightly increased in Cad erythrocyte membranes. These results suggest that the glycoprotein has a substantial content of O-glycans. The glycoprotein appears to be absent from, or grossly altered in, the erythrocytes of two individuals with the rare Inab phenotype.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-14170409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-14907713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-2424433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-2429846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-2579328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-3537734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-3756102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-3821520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-3946000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-4473996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-5072588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-521666,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-5484815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-5727552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6129975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6190803,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-62283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6345670,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6415175,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6466322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6466869,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6601483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6605304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6712635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6807697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6812050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-6968681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-7073987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-7123631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-7161507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-788105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3679286-83233
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0019-2805
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-13
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3679286-Antibodies, Monoclonal,
pubmed-meshheading:3679286-Antibody Specificity,
pubmed-meshheading:3679286-Antigens, Surface,
pubmed-meshheading:3679286-Blood Group Antigens,
pubmed-meshheading:3679286-Blood Platelets,
pubmed-meshheading:3679286-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3679286-Erythrocytes,
pubmed-meshheading:3679286-Glycoproteins,
pubmed-meshheading:3679286-Humans,
pubmed-meshheading:3679286-Leukemia, Lymphoid,
pubmed-meshheading:3679286-Leukocytes,
pubmed-meshheading:3679286-Molecular Weight,
pubmed-meshheading:3679286-Phenotype
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pubmed:year |
1987
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pubmed:articleTitle |
A human cell-surface glycoprotein that carries Cromer-related blood group antigens on erythrocytes and is also expressed on leucocytes and platelets.
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pubmed:affiliation |
Western Regional Blood Transfusion Centre, Southmead, Bristol, London, U.K.
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pubmed:publicationType |
Journal Article
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