Linked Life Data

3666685

Source:http://linkedlifedata.com/resource/pubmed/id/3666685

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-12-2
pubmed:abstractText
A cooperative behavior, coordinated shuttling by pairs of laboratory rats in a rectangular chamber, can be influenced strongly by an interaction between housing and sex. Males and females learn readily when housed together socially, but individual housing ("isolation") causes severe deficits selectively in males. The aim of the present study was to examine the role of testosterone in the differential effects of housing on cooperation learning. Males of a Sprague-Dawley derived strain were housed socially or individually and treated daily in one of three ways (six groups, n = 6 per group): (1) castrated, injected with oil vehicle (without testosterone); (2) castrated, injected with 500 micrograms testosterone propionate (exogenous TP); and (3) sham operated, injected with oil (intact, endogenous testosterone). Socially housed pairs learned readily in all treatment groups, using strategies of coordination in which stereotyped contact or aggressive interactions were interpolated. Individual housing was associated with a deficit, but only in the TP-treated and intact groups in which some pairs either did not learn or performed poorly. The deficit was associated with violent fighting and extreme and stable differentiation into dominants and subordinates, the latter exhibiting prolonged freezing. Oil-treated castrates, when housed individually, were unimpaired and actually surpassed their socially housed counterparts on some measures. Their success was associated with an increase only in low-level aggression. The housing-hormone interaction in male rats suggests that testosterone influences the capacity to develop cooperative behavior by modulating both aggression and its consequences for the relationship between partners. The use of social interaction models, including cooperation, for the study of behavior-hormone interactions was also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0018-506X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
310-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Cooperative social coordination and aggression in male laboratory rats: effects of housing and testosterone.
pubmed:affiliation
Netherlands Institute for Brain Research.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't