Linked Life Data

3665968

Source:http://linkedlifedata.com/resource/pubmed/id/3665968

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-12-8
pubmed:abstractText
195mAu, an ultrashort-lived (physical half life = 30.5 s) generator-produced radionuclide, has been used in an animal model to study, by gamma camera techniques, the peripheral effects of the vasoactive drugs norepinephrine and sodium nitroprusside systemically administered or epinephrine (intraarterially) injected at various concentrations. According to the results obtained by the analysis of time activity curves generated from areas of interest drawn on the proximal and distal parts of the limbs, the well known hemodynamic changes induced by these drugs, vasoconstriction (resulting in a decrease of the distal activity recorded), or vasodilatation (shortening the time of radioactivity appearance), could be observed. It is concluded that gamma camera techniques using the ultrashort lived radionuclide 195mAu allow the in vivo study of the effects of vasoactive drugs in an animal model and potentially in clinical situations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0340-6997
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-4
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
In vivo animal demonstration of the effect of vasoactive drugs using 195mAu and gamma camera techniques.
pubmed:affiliation
Department of Nuclear Medicine, Hospital of Anderlecht, Brussels, Belgium.
pubmed:publicationType
Journal Article