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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1987-10-15
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pubmed:abstractText |
The symptoms of acute poisoning after accidental administration of ten times the usually prescribed dosage of caffeine in a premature infant included the following neurological signs: incessant tremors, hypertonia, continuous opisthotonos posture, whining and crying and digestive disturbances. The very high serum caffeine levels, 160 mg/l, determined 66 hours after the first administration was confirmed by the very high cerebrospinal fluid caffeine concentration 115 mg/l. Two exchange transfusions performed at an interval of 16 hours produced a large decrease in serum caffeine levels of approximately 40 mg/l each time, and a similar decrease in the cerebrospinal fluid concentration. The clinical status of the infant improved very rapidly and the child's psychomotor development was normal at 3 months of age.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0001-656X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
679-81
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:3630690-Acute Disease,
pubmed-meshheading:3630690-Caffeine,
pubmed-meshheading:3630690-Citrates,
pubmed-meshheading:3630690-Drug Combinations,
pubmed-meshheading:3630690-Exchange Transfusion, Whole Blood,
pubmed-meshheading:3630690-Humans,
pubmed-meshheading:3630690-Infant, Newborn,
pubmed-meshheading:3630690-Infant, Premature, Diseases,
pubmed-meshheading:3630690-Male
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pubmed:year |
1987
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pubmed:articleTitle |
Treatment of caffeine intoxication by exchange transfusion in a newborn.
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pubmed:publicationType |
Journal Article,
Case Reports
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