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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1987-10-2
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pubmed:abstractText |
One thousand five hundred and seventeen HBsAg carriers from different cities of Argentina were studied for the presence of anti-Delta antibody (anti-HDV) in their sera. One thousand one hundred and sixty-eight were volunteer blood donors and 349 were patients with liver disease. Different liver diseases were diagnosed by clinical, biochemical, and histological parameters. Among blood donors, 16 (1.4%) were positive for the antibody and none was Delta-antigen positive. In 130 patients with acute hepatitis, one (0.77%) was positive for anti-HDV, as well as three (2.22%) out of 135 patients with chronic active hepatitis (CAH), and three (5.77%) out of 52 patients with cirrhosis (C). No anti-HDV positive was found among seven fulminant hepatitis (FH) cases. The presence of HBeAg and anti-HBe was studied in anti-HDV positive sera; eleven (69%) volunteer blood donors were anti-HBe positive, and five (31%) were HBeAg positive. HBeAg was positive in the three CAH cases, and in one out of three C Cases with anti-HDV positive. Hepatitis Delta antigen was also positive in the hepatocytic nuclei in the three patients with C and two of the three CAH cases. The present results show that Delta infection is rare among blood donors in Argentina. A small variation without statistical significance could be found within different geographical areas. Among patients with HBsAg related liver disease, the presence of HDV markers was also low.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0146-6615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
257-62
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pubmed:dateRevised |
2006-4-13
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pubmed:meshHeading |
pubmed-meshheading:3625173-Adolescent,
pubmed-meshheading:3625173-Adult,
pubmed-meshheading:3625173-Argentina,
pubmed-meshheading:3625173-Blood Donors,
pubmed-meshheading:3625173-Carrier State,
pubmed-meshheading:3625173-Female,
pubmed-meshheading:3625173-Hepatitis Antibodies,
pubmed-meshheading:3625173-Hepatitis B,
pubmed-meshheading:3625173-Hepatitis B Surface Antigens,
pubmed-meshheading:3625173-Hepatitis B e Antigens,
pubmed-meshheading:3625173-Hepatitis D,
pubmed-meshheading:3625173-Hepatitis Delta Virus,
pubmed-meshheading:3625173-Humans,
pubmed-meshheading:3625173-Liver Diseases,
pubmed-meshheading:3625173-Male,
pubmed-meshheading:3625173-Middle Aged
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pubmed:year |
1987
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pubmed:articleTitle |
Anti-delta antibody in various HBsAg positive Argentine populations.
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pubmed:publicationType |
Journal Article
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