Linked Life Data

3621522

Source:http://linkedlifedata.com/resource/pubmed/id/3621522

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-10-7
pubmed:abstractText
Twenty-three Ionescu-Shiley standard bovine pericardial bioprostheses (15 aortic, seven mitral, and one tricuspid) removed at surgery from 21 adults, 28 to 75 years old (mean 55 at reoperation), were examined after functioning for as long as 84 months (mean 26). Reoperation was necessitated by active or healed endocarditis (10 valves), paravalvular leak (three), structural deterioration (eight), and other causes (two). Valves with degenerative dysfunction functioned 32 to 84 months (mean 68). Six had intrinsic cuspal calcification, one with stenosis, and there was regurgitation through secondary cuspal defects in five. Six valves had cuspal defects clearly associated with commissural sutures ("alignment stitches") unique to this valve design. One valve had a large basal cuspal tear. Other prominent pathologic features included gross cuspal thickening and mild stretching and microscopic deep fluid insudation, separation of collagen bundles, and mononuclear inflammation. Thus, structural disruption due to calcific tissue degeneration and design-related cuspal tears or commissural perforations are the predominant modes of degenerative failure of Ionescu-Shiley standard bovine pericardial valves.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0009-7322
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
618-27
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Causes of failure and pathologic findings in surgically removed Ionescu-Shiley standard bovine pericardial heart valve bioprostheses: emphasis on progressive structural deterioration.
pubmed:publicationType
Journal Article, Comparative Study