Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-8-31
pubmed:abstractText
Six-month oral chronic toxicity study and two-month recovery tests on rokitamycin (TMS-19-Q) were performed in Beagle dogs at daily doses of 90, 180 and 360 mg/kg. The results were summarized as follows: No death occurred to any animals in these experiments. In higher dosage groups (180 and 360 mg/kg), vomiting, salivation and reduction of body weight gain with decrease in food intake were observed. Body temperature and pulse rate were normal, and ECG, sperm and vaginal smear tests, urinalysis, blood and biochemical examinations also revealed normal values. No marked changes in organ weights, necropsy, histopathological and electron microscopic observations were detected.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0368-2781
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
561-87
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Chronic toxicity and recovery tests of rokitamycin in beagle dogs].
pubmed:publicationType
Journal Article, English Abstract