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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1987-8-31
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pubmed:abstractText |
The effect of the internal pH on the rate of 36Cl- uptake and efflux was measured. While the rate of 36Cl- uptake by the antiport increased almost 10-fold over a narrow pH range in a number of cell lines, in other cells the pH-induced increase was considerably less. With increasing pH, the rate of 36Cl- efflux into chloride-free buffers increased strongly over a narrow pH range in all cell lines studied. Two groups of cell lines appeared, one group where the half-maximal increase in uptake and efflux rate was at pH 7.0-7.1 and another group where the corresponding values were 0.2-0.4 pH unit higher. The stoichiometry between chloride influx and chloride-stimulated efflux was close to 1:1 under various conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0006-2960
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2778-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3606992-Animals,
pubmed-meshheading:3606992-Biological Transport, Active,
pubmed-meshheading:3606992-Cell Line,
pubmed-meshheading:3606992-Chlorides,
pubmed-meshheading:3606992-HeLa Cells,
pubmed-meshheading:3606992-Humans,
pubmed-meshheading:3606992-Hydrogen-Ion Concentration,
pubmed-meshheading:3606992-Kinetics
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pubmed:year |
1987
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pubmed:articleTitle |
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines.
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pubmed:publicationType |
Journal Article,
Comparative Study
|