Linked Life Data

3602020

Source:http://linkedlifedata.com/resource/pubmed/id/3602020

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-8-11
pubmed:abstractText
A double-blind, double-dummy study design was used to compare the efficacy and tolerance of naproxen with that of pirprofen in the treatment of osteoarthritis. Sixty patients were assigned randomly to receive either 500 mg naproxen twice daily or 400 mg pirprofen twice daily for 4 weeks. Both groups were similar in all respects except age, which was significantly greater in the naproxen-treated patients than in the pirprofen-treated patients. Both treatments yielded statistically significant improvement in duration of stiffness after inactivity, global pain, pain on full passive movement, pain during a selected activity, and physicians' and patients' assessments of overall arthritic condition. There were no significant differences between the two groups in either the incidence or the severity of adverse effects of the drugs, most of which involved gastro-intestinal disturbances. Both medications were shown to be well tolerated, acceptable, and effective for treating osteoarthritis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0308-051X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
16-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Efficacy and tolerance of naproxen versus pirprofen in the treatment of patients with osteoarthritis.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial