Linked Life Data

3580418

Source:http://linkedlifedata.com/resource/pubmed/id/3580418

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-7-14
pubmed:abstractText
The kinetic parameters of binding and hydroxylation of hydrophobic substrate 3,4-benzpyrene have been studied in liver microsomes of untreated and 3-methylcholanthrene treated mice. The reaction of benzpyrene-hydroxylase has been established to be described by hyperbolic curve, which characterizes the dependence of [ES] and d(P)/dt on [E0] for reactions in biphasic system. A key role of microsomal membraneous phospholipids has been revealed in competitive inhibition of 3,4-benzpyrene hydroxylation. For the adequate application of Michaelis--Menten theory for benzpyrene-hydroxylation reaction a modified method of 3,4-benzpyrene-hydroxylation in the samples with low content of protein in microsomal fraction is suggested.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0470-4606
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Kinetic characteristics of 3,4-benzpyrene hydroxylation in the liver microsomes of mice].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract