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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-5-21
|
pubmed:abstractText |
This is the first report of glomerular disease in a 13-year-old boy who was a carrier of hepatitis B virus both mesangial IgA and subepithelial IgG deposits in the glomeruli at the same time. The clinical findings resembled those of IgA nephropathy. On electron microscopy, electron-dense deposits were identified not only in the mesangium but also on the epithelial side of the glomerular basement membrane. Immunofluorescence and immunoperoxidase staining demonstrated hepatitis B surface antigen and hepatitis B core antigen in the glomeruli but hepatitis B e antigen was not detected. Our findings suggest hepatitis B virus antigens have a pathogenetic role in the simultaneous development of these two glomerulopathies.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0046-8177
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
411-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3557446-Adolescent,
pubmed-meshheading:3557446-Glomerulonephritis,
pubmed-meshheading:3557446-Glomerulonephritis, IGA,
pubmed-meshheading:3557446-Hepatitis B,
pubmed-meshheading:3557446-Hepatitis B Surface Antigens,
pubmed-meshheading:3557446-Humans,
pubmed-meshheading:3557446-Kidney Glomerulus,
pubmed-meshheading:3557446-Male
|
pubmed:year |
1987
|
pubmed:articleTitle |
IgA nephropathy and membranous nephropathy associated with hepatitis B surface antigenemia.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|