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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1987-3-3
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pubmed:abstractText |
Carboplatin (JM8), a new cisdiamminodichloroplatin (CDDP) analogue, has exhibited the same antitumor as CDDP. In our pilot study, aiming at optimizing the dosage of this drug in a combination regimen with other chemotherapics, we planned to evaluate the existence of drug related damage on cochleo-vestibular structures. The study was performed on 9 patients suffering from advanced ovarian carcinoma. The results obtained in our study showed that patients undergoing carboplatin chemotherapy do not require an audiometric check-up. In order to assess definitely the existence of vestibular toxicity of this drug, larger studies planned to test JM8 in a high-dosage regimen are desirable.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0392-906X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
411-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3542253-Aged,
pubmed-meshheading:3542253-Antineoplastic Agents,
pubmed-meshheading:3542253-Carboplatin,
pubmed-meshheading:3542253-Cochlea,
pubmed-meshheading:3542253-Female,
pubmed-meshheading:3542253-Hearing Disorders,
pubmed-meshheading:3542253-Hearing Tests,
pubmed-meshheading:3542253-Humans,
pubmed-meshheading:3542253-Middle Aged,
pubmed-meshheading:3542253-Organoplatinum Compounds,
pubmed-meshheading:3542253-Ovarian Neoplasms,
pubmed-meshheading:3542253-Vestibule, Labyrinth
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pubmed:year |
1986
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pubmed:articleTitle |
Evaluation of the cochleovestibular function in patients treated with carboplatin for ovarian carcinoma.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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