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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1978-9-25
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pubmed:abstractText |
In order to elucidate some of the factors responsible for the high rate of nosocomial infection associated with neonatal intensive care, we studied bacterial colonization in 63 infants admitted to a neonatal intensive care unit. In a six-month period, cultures of nose, throat, umbilicus, and stool were obtained on admission and every three days from all infants staying in the NICU greater than or equal to 3 days. Study infants did not develop "normal" aerobic flora. Forty-eight percent of infants grew Escherichia coli from stool, but 52% had stool colonization with Klebsiella, Enterobacter, or Citrobacter, the only other Enterobacteriaceae encountered. KEC were also isolated from throat, nose, and umbilicus in 22%, 22%, and 24% of patients, respectively. The risk of stool colonization with KEC increased with duration of hospitalization: 2% of infants were colonized on admission, 60% after 15 days, and 91% after 30 days. Stool colonization with E. coli seemed to protect infants from colonization with other gram-negative bacilli. Thirteen of 20 infants, however, developed pharyngeal GNB colonization in spite of pre-existing abundant growth of alpha streptococci. Antibiotic therapy for greater than 3 days was associated with the isolation of KEC in stool and GNB in the throat, but birth weight less than 2,500 gm and lack of breast milk feedings were not.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
288-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:353239-Boston,
pubmed-meshheading:353239-Citrobacter,
pubmed-meshheading:353239-Cross Infection,
pubmed-meshheading:353239-Enterobacter,
pubmed-meshheading:353239-Enterobacteriaceae Infections,
pubmed-meshheading:353239-Escherichia coli,
pubmed-meshheading:353239-Feces,
pubmed-meshheading:353239-Female,
pubmed-meshheading:353239-Humans,
pubmed-meshheading:353239-Infant, Newborn,
pubmed-meshheading:353239-Infant, Newborn, Diseases,
pubmed-meshheading:353239-Intensive Care Units,
pubmed-meshheading:353239-Klebsiella,
pubmed-meshheading:353239-Nose,
pubmed-meshheading:353239-Pharynx,
pubmed-meshheading:353239-Pregnancy,
pubmed-meshheading:353239-Umbilicus
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pubmed:year |
1978
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pubmed:articleTitle |
Bacterial colonization of neonates admitted to an intensive care environment.
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pubmed:publicationType |
Journal Article
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