Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1986-7-25
|
| pubmed:abstractText |
The in vivo response of Plasmodium falciparum to chloroquine and to pyrimethamine/sulfadoxine was studied for seven days in schoolchildren from two villages 30 to 40 km north of Dar es Salaam. Standard therapeutic regimen of chloroquine (25 mg base kg-1) failed to clear parasitaemia in 17 of 62 (27%) treated subjects. In contrast, standard treatment with pyrimethamine/sulfadoxine cleared the parasitaemia in all 44 treated subjects within five days. Hence, in the studied area, the therapeutic effect of sulfadoxine/pyrimethamine was superior to that of chloroquine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0003-4983
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
80
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
7-11
|
| pubmed:dateRevised |
2009-5-18
|
| pubmed:meshHeading |
pubmed-meshheading:3524485-Adolescent,
pubmed-meshheading:3524485-Child,
pubmed-meshheading:3524485-Chloroquine,
pubmed-meshheading:3524485-Drug Therapy, Combination,
pubmed-meshheading:3524485-Humans,
pubmed-meshheading:3524485-Malaria,
pubmed-meshheading:3524485-Plasmodium falciparum,
pubmed-meshheading:3524485-Pyrimethamine,
pubmed-meshheading:3524485-Sulfadoxine,
pubmed-meshheading:3524485-Sulfanilamides,
pubmed-meshheading:3524485-Tanzania,
pubmed-meshheading:3524485-Time Factors
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Sensitivity in vivo of Plasmodium falciparum to chloroquine and pyrimethamine/sulfadoxine in a coastal area of Tanzania.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|