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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1986-5-1
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pubmed:abstractText |
Monoclonal antibodies to the major Plasmodium falciparum merozoite surface coat and rhoptry antigens were produced. A combination of the affinity-purified polypeptides with Freund complete adjuvant which was given three times completely protected an Aotus lemurinus azure (karotype VI) monkey against homologous challenge; however, immunization with the same polypeptides with a muramyl dipeptide derivative [MDP-Lys(L18)] did not protect a second Aotus monkey, even though comparable high antibody titers were induced.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-103100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-120768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-2578540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-2995820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-3881529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-3887156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-3889058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-3894564,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-4044097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-406671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6090934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6161311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6205267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6341226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6346229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6355363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6360901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6361573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6364136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6374450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6379450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6381635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6381636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6383858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6391218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6393131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6752328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6757400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-69057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-6955305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-7005690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3514459-99814
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3514459-Acetylmuramyl-Alanyl-Isoglutamine,
pubmed-meshheading:3514459-Adjuvants, Immunologic,
pubmed-meshheading:3514459-Animals,
pubmed-meshheading:3514459-Antibodies, Monoclonal,
pubmed-meshheading:3514459-Antibody Formation,
pubmed-meshheading:3514459-Antigens, Protozoan,
pubmed-meshheading:3514459-Aotus trivirgatus,
pubmed-meshheading:3514459-Malaria,
pubmed-meshheading:3514459-Mice,
pubmed-meshheading:3514459-Molecular Weight,
pubmed-meshheading:3514459-Plasmodium falciparum,
pubmed-meshheading:3514459-Vaccination
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pubmed:year |
1986
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pubmed:articleTitle |
Induction of protective immunity to monoclonal-antibody-defined Plasmodium falciparum antigens requires strong adjuvant in Aotus monkeys.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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