Linked Life Data

3512793

Source:http://linkedlifedata.com/resource/pubmed/id/3512793

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-4-11
pubmed:abstractText
Immunocytochemical techniques were used to examine the synaptic relations of inhibitory interneurons in the developing rabbit hippocampus. Glutamic acid decarboxylase (GAD), the synthesizing enzyme for the inhibitory neurotransmitter GABA, was found in interneurons of immature (8 d old) as well as mature (30 d old) tissue. GAD-immunoreactivity was seen in somata, dendrites, and axon terminals of interneurons at both ages. Electron-microscopic examination revealed that GAD-positive "terminals" in immature tissue were often not associated with the usual synaptic specializations, but were rather in simple apposition to the "postsynaptic" element. In mature tissue, GAD-positive terminals made symmetric contacts primarily with pyramidal cell somata, initial segments, and proximal dendrites. In addition, GAD-positive terminals synapsed onto both GAD-positive and GAD-negative interneuron profiles.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0270-6474
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
541-52
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Glutamic acid decarboxylase (GAD) immunocytochemistry of developing rabbit hippocampus.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.