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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0009647,
umls-concept:C0035647,
umls-concept:C0206427,
umls-concept:C0262485,
umls-concept:C0330095,
umls-concept:C0681841,
umls-concept:C1280500,
umls-concept:C1552915,
umls-concept:C1704638,
umls-concept:C1705186,
umls-concept:C1880177,
umls-concept:C1947942,
umls-concept:C2347970,
umls-concept:C2347971,
umls-concept:C2350017
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pubmed:issue |
6
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pubmed:dateCreated |
1987-11-18
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pubmed:abstractText |
The oscillatory potentials (OPs) of the human electroretinogram (ERG) are smaller in response to the initial flash of a series than to subsequent flashes. To investigate a possible rod system contribution to this "conditioning flash effect," we have examined OPs in normals and rod monochromats. The OPs recorded from rod monochromats were similar to those recorded from normals under test conditions that selectively stimulate rods. However, under conditions that in normals stimulate both rods and cones and that result in maximal amplitude of the OPs, the rod monochromats exhibit markedly reduced OPs. This finding suggests that the initial (conditioning) flash operates by adapting the rod system contribution to the OPs, so that the OPs in response to subsequent flashes result primarily from the cone system. In agreement with this hypothesis, the conditioning flash effect did not occur when flashes were presented against a background which eliminated the rod system response nor during the cone plateau phase of dark adaptation.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0042-6989
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
859-66
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:3499028-Color Vision Defects,
pubmed-meshheading:3499028-Dark Adaptation,
pubmed-meshheading:3499028-Electroretinography,
pubmed-meshheading:3499028-Humans,
pubmed-meshheading:3499028-Photic Stimulation,
pubmed-meshheading:3499028-Photometry,
pubmed-meshheading:3499028-Photoreceptor Cells
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pubmed:year |
1987
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pubmed:articleTitle |
Rod and cone system contributions to oscillatory potentials: an explanation for the conditioning flash effect.
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pubmed:affiliation |
Department of Ophthalmology, University of Illinois College of Medicine, Chicago 60612.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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