Linked Life Data

3491801

Source:http://linkedlifedata.com/resource/pubmed/id/3491801

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-2-2
pubmed:abstractText
Fifty-nine pregnant Wistar strain rats were sham irradiated or subjected to a 0.1 or 0.2 Gy exposure of X-radiation on the 9th or 17th day of gestation. Twenty-seven of the females were killed at term for teratologic analysis. The remaining mothers raised their young. At 60 days of age the 252 offsprings were randomly assigned three of six tests: open field, swimming, hanging, activity wheel, water T-maze, or conditioned avoidance response. Male offspring exposed at the 0.2 Gy level exhibited retarded growth only during the first few weeks of postnatal life. Female offspring exposed on the 17th day to 0.2 Gy X-radiation were growth retarded throughout the test period. Postnatal growth rates, however, were not significantly different between the irradiated and control groups. There were no significant alterations in adult behaviour due to prenatal X-irradiation. There were sex differences in activity wheel and forelimb hanging performance, unrelated to radiation exposure. These results indicate that prenatal low level X-irradiation on the 9th or 17th day of gestation does not result in significant alterations in adult behavioural performance in the rat, but prenatal growth retardation persists postnatally. Growth may be a more sensitive indicator of the effects of prenatal exposure to X-radiation than postnatal behaviour.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0020-7616
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1069-81
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Studies concerning the effects of low level prenatal X-irradiation on postnatal growth and adult behaviour in the Wistar rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.