Linked Life Data

3491490

Source:http://linkedlifedata.com/resource/pubmed/id/3491490

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1987-1-9
pubmed:abstractText
Various gram-positive and gram-negative bacteria were tested for their ability to induce antibody secretion in human blood cell cultures. Total and specific immunoglobulin levels in the culture supernatants were quantitated with enzyme-linked immunosorbent assays (ELISA). All the twelve strains used stimulated IgM and IgG secretion in adult mononuclear cell cultures. With the four strains tested, also umbilical cord blood cells produced IgM. Specific antibodies directed against two bacteria were sought in adult and newborn cell culture but none were found. Bacterium-induced antibody synthesis thus seemed to be polyclonal. Experiments with purified T and B lymphocytes showed that bacterium-driven antibody formation was T-cell dependent.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0108-0202
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
131-6
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Bacteria are polyclonal T-dependent stimulants of immunoglobulin formation.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't