Linked Life Data

3489096

Source:http://linkedlifedata.com/resource/pubmed/id/3489096

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-10-23
pubmed:abstractText
Investigations were carried out on the influence of progesterone and murine trophoblast culture supernatants on the capacity of lymphocytes to form aggregates (clusters), an important feature in immunologic recognition and response. Both progesterone and trophoblast supernatants inhibited this cluster formation in a dose-dependent way. The effect of trophoblast supernatants appeared to be mediated mainly by progesterone since they lost their inhibitory effect on the cluster formation after treatment with anti-progesterone serum (APS). Preparations with I1-2 activity of rat and mouse origin could either prevent or restore the suppressive effect of both progesterone and trophoblast supernatants on lymphocyte aggregation. The interference with lymphocyte interaction by trophoblast may represent one of the mechanisms by which the fetal allograft is protected against maternal recognition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0165-0378
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-21
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Inhibition of lymphocyte aggregation by progesterone.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't