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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1986-6-18
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pubmed:abstractText |
High doses of retinol produce hyperostotic lesions in animals and humans. In this study we measured in fasting subjects and 5 hours after administering 50,000 IU of retinol, levels in the serum of retinol, retinol-binding protein (RBP) and prealbumin in 35 hyperostotic subjects (HVA) and 22 control subjects. Retinol levels were equally high after fasting and after consumption of vitamin A (p 0.01). The levels of retinol-binding protein and prealbumin increase in parallel, such that the molar ratios of retinol to retinol-binding protein or to prealbumin are not changed. Taken with literature data, those of the present study indicate that vitamin A is responsible for the production of hyperostotic lesions.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0035-2659
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
143-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3486449-Adult,
pubmed-meshheading:3486449-Aged,
pubmed-meshheading:3486449-Female,
pubmed-meshheading:3486449-Humans,
pubmed-meshheading:3486449-Hyperostosis, Diffuse Idiopathic Skeletal,
pubmed-meshheading:3486449-Male,
pubmed-meshheading:3486449-Middle Aged,
pubmed-meshheading:3486449-Prealbumin,
pubmed-meshheading:3486449-Retinol-Binding Proteins,
pubmed-meshheading:3486449-Spinal Osteophytosis,
pubmed-meshheading:3486449-Vitamin A
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pubmed:year |
1986
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pubmed:articleTitle |
[Metabolism of vitamin A in Forestier-Rotès-Quérol hyperostosis].
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pubmed:publicationType |
Journal Article,
English Abstract
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