Linked Life Data

3436419

Source:http://linkedlifedata.com/resource/pubmed/id/3436419

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-4-7
pubmed:abstractText
The antinociceptive activity of several enkephalin and kyotorphine analogues having nonproteinogenic nucleoamino acids: adenyl alanine, thyminyl alanine or uracilyl alanine in their structure was studied by the method of tail clip stimulation in mice. Kyotorphine and its analogues administered intracisternally to mice were found to inhibit the nociceptive responses only at doses similar to toxic ones. At the same time among nucleoamino acid analogues of enkephalins compounds were detected which possessed the antinociceptive activity not only at intracisternal administration but at intravenous injection as well. Some structure-activity relationships of the compounds tested are discussed.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-8318
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
20-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Analgesic activity of nucleoamino acid analogs of neuropeptides injected intracisternally and intravenously in mice].
pubmed:publicationType
Journal Article, English Abstract