| pubmed-article:3435498 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0032961 | lld:lifeskim |
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| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0022925 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0205054 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0031715 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C1415615 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
| pubmed-article:3435498 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:3435498 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3435498 | pubmed:dateCreated | 1988-3-15 | lld:pubmed |
| pubmed-article:3435498 | pubmed:abstractText | 1. The expressed and total (completely dephosphorylated) activities of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase were measured in microsomal fractions isolated from cold-clamped liver samples from female rats in various stages of the reproductive cycle. 2. There was little change in total HMG-CoA reductase activity during pregnancy and early lactation, but after 2 days post partum there was a marked increase in total activity. 3. The expressed/total activity ratio of HMG-CoA reductase showed a profound decrease during the last 2 days of pregnancy. The fraction of the enzyme in the active form increased progressively during the first 2 days of lactation. 4. The combined effect of these changes was that the expressed activity of HMG-CoA reductase changed in parallel with the known changes in the hepatic rate of cholesterogenesis during pregnancy and lactation in vivo. | lld:pubmed |
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| pubmed-article:3435498 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3435498 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3435498 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3435498 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3435498 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3435498 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:3435498 | pubmed:issn | 0264-6021 | lld:pubmed |
| pubmed-article:3435498 | pubmed:author | pubmed-author:ZammitV AVA | lld:pubmed |
| pubmed-article:3435498 | pubmed:author | pubmed-author:EasomR ARA | lld:pubmed |
| pubmed-article:3435498 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3435498 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:3435498 | pubmed:volume | 248 | lld:pubmed |
| pubmed-article:3435498 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3435498 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3435498 | pubmed:pagination | 993-6 | lld:pubmed |
| pubmed-article:3435498 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3435498 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3435498 | pubmed:articleTitle | Role of reversible phosphorylation in mediating changes in the activity of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase during pregnancy and lactation in the rat. | lld:pubmed |
| pubmed-article:3435498 | pubmed:affiliation | Hannah Research Institute, Ayr, Scotland, U.K. | lld:pubmed |
| pubmed-article:3435498 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3435498 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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