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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1988-3-3
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pubmed:abstractText |
In this open study patients with advanced Parkinson's disease, who experienced pronounced fluctuations in symptoms while on standard L-dopa, were switched from Madopar/Sinemet to Madopar HBS. The dosage was adjusted until optimal response was obtained. The effect was unsatisfactory in 4 cases and side effects intervened in another 2. The remaining 16 patients exhibited substantial and frequently significant improvements with regard to both akinetic and dyskinetic phenomena. L-Dopa dosage was increased in all cases, and addition of standard L-dopa was required in one third of the cases. These benefits continued in the majority of patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
68-72
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pubmed:dateRevised |
2009-12-23
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pubmed:meshHeading |
pubmed-meshheading:3428310-Adult,
pubmed-meshheading:3428310-Aged,
pubmed-meshheading:3428310-Benserazide,
pubmed-meshheading:3428310-Delayed-Action Preparations,
pubmed-meshheading:3428310-Drug Combinations,
pubmed-meshheading:3428310-Female,
pubmed-meshheading:3428310-Humans,
pubmed-meshheading:3428310-Hydrazines,
pubmed-meshheading:3428310-Levodopa,
pubmed-meshheading:3428310-Male,
pubmed-meshheading:3428310-Middle Aged,
pubmed-meshheading:3428310-Movement Disorders,
pubmed-meshheading:3428310-Parkinson Disease
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pubmed:year |
1987
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pubmed:articleTitle |
Madopar HBS: slow-release levodopa and benserazide in parkinsonian patients presenting marked fluctuations in symptoms on standard L-dopa treatment.
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pubmed:affiliation |
Department of Neurology, University Hospital Hvidovre, Denmark.
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pubmed:publicationType |
Journal Article
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