Linked Life Data

341428

Source:http://linkedlifedata.com/resource/pubmed/id/341428

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-3-29
pubmed:abstractText
We have studied the immune response of six patients admitted to the San Diego Regional Burn Treatment Center for treatment of major thermal injuries. Three of the patients retained skin allografts from unrelated donors for long periods (37, 47, and 67 days) while the remaining three rejected their grafts at 8, 10, and 12 days, respectively. Allograft survival appeared to be directly related to the immunosuppressive activity of patient sera on phytohemagglutinin-induced blastogenesis of normal lymphocytes in vitro. Survival did not appear to be related to patient lymphocyte number or reduced reactivity, nor was graft prolongation accompanied by reduced immunoglobulin production. Our work thus supports the hypothesis that spontaneous immunosuppression may be of importance in the clinical consequences of thermal injuries.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0041-1337
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Prolonged survival of human skin allografts following thermal injury.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.