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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0008100,
umls-concept:C0021247,
umls-concept:C0042839,
umls-concept:C0042874,
umls-concept:C0178602,
umls-concept:C0205803,
umls-concept:C0240919,
umls-concept:C0442027,
umls-concept:C0449438,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1705493,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
2
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pubmed:dateCreated |
1988-9-9
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pubmed:abstractText |
Vitamin A and E status was studied in five groups (satisfactory growth, reduced growth, night blindness, Bitot's spots, and corneal xerosis) of rural Indonesian preschool children. All groups except corneal xerosis showed satisfactory weight-height ratios. Initial serum retinol values were less than 0.35 mumol/L in 34% of all children. After oral administration of 24.4 mumol vitamin A, mean serum retinol values rose from 0.42 to 0.70 mumol/L at 10 d. After oral treatment of children with 244 or 314 mumol vitamin A, mean serum retinol remained greater than 0.56 mumol/L for 165 d. Of particular note were the low mean initial serum alpha-tocopherol concentrations (6.3 mumol/L) and alpha-tocopherol-total lipid ratios (1.5 mumol/g). Total serum lipids fell in the normal range. Oral administration of 84 mumol vitamin E raised serum alpha-tocopherol and alpha-tocopherol-total-lipid ratios by 46 and 44%, respectively. Thus, vitamin E inadequacy, which impairs vitamin A absorption and storage, may well contribute to the high incidence of clinical vitamin A deficiency in West Javan children.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
279-85
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3407606-Administration, Oral,
pubmed-meshheading:3407606-Child, Preschool,
pubmed-meshheading:3407606-Female,
pubmed-meshheading:3407606-Humans,
pubmed-meshheading:3407606-Indonesia,
pubmed-meshheading:3407606-Lipids,
pubmed-meshheading:3407606-Male,
pubmed-meshheading:3407606-Nutritional Status,
pubmed-meshheading:3407606-Vitamin A,
pubmed-meshheading:3407606-Vitamin E
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pubmed:year |
1988
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pubmed:articleTitle |
Vitamin A and vitamin E status of rural preschool children in West Java, Indonesia, and their response to oral doses of vitamin A and of vitamin E.
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pubmed:affiliation |
Division of Biochemical Nutrition, Nutrition Research and Development Center, Bogor, Indonesia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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