Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-9-21
|
pubmed:abstractText |
Late systemic-allergic reactions (defined as occurring between 30 minutes and 6 hours after injection) to inhalant allergen immunotherapy were prospectively studied in four allergy treatment centers; 35,674 injections were administered to 712 patients. Twenty-nine patients (4% of all patients) experienced 33 late reactions. Fifty-six injections (0.16% of all injections) were associated with the 33 late reactions. The most common clinical manifestation of a late reaction was urticaria. However, objective respiratory airway involvement, as manifested by wheezing and/or stridor, occurred in 10 (27%) of the late reactions. Delayed reactions involving wheezing and/or stridor were only related to injections from maintenance vials, and all these more severe reactions occurred no later than 60 minutes after injection. We conclude that late systemic-allergic reactions account for a significant percent of the total number of systemic-allergic reactions to inhalant allergen immunotherapy. It is our belief that a 60-minute postinjection waiting period for injections administered from maintenance vials of extract would enhance the safety of inhalant allergen immunotherapy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0091-6749
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
82
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
287-90
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:3403869-Female,
pubmed-meshheading:3403869-Humans,
pubmed-meshheading:3403869-Hypersensitivity, Delayed,
pubmed-meshheading:3403869-Immunotherapy,
pubmed-meshheading:3403869-Injections,
pubmed-meshheading:3403869-Male,
pubmed-meshheading:3403869-Respiratory Sounds,
pubmed-meshheading:3403869-Time Factors,
pubmed-meshheading:3403869-Urticaria
|
pubmed:year |
1988
|
pubmed:articleTitle |
Late systemic-allergic reactions to inhalant allergen immunotherapy.
|
pubmed:affiliation |
Allergy and Immunization Clinic, Womack Army Community Hospital, Fort Bragg, N.C.
|
pubmed:publicationType |
Journal Article
|