Linked Life Data

3354681

Source:http://linkedlifedata.com/resource/pubmed/id/3354681

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Pt 1
pubmed:dateCreated
1988-5-11
pubmed:abstractText
Whole-thickness everted jejunal rings were used to measure uptake of L-tyrosine (L-Tyr), L-phenylalanine (L-Phe), and L-tryptophan (L-Trp) in 6-, 12-, and 24-mo-old rats. The rate of uptake of all three amino acids (1 mM) was significantly reduced after 20 min of incubation in 24-mo-old compared with 6-mo-old rats. Results of influx (2 min) of 0.5-40.0 mM L-Phe and L-Trp suggested an increased affinity but decreased capacity for the transporter with age; these differences were significant for L-Trp (P less than 0.05). Respective values for apparent Kt and Vmax were the following: L-Phe 6-mo-old rats, 5.46 mM and 1.03 mumol.g-1.2 min-1; 24-mo-old rats, 2.54 mM and 0.51 mumol.g-1.2 min-1; L-Trp 6-mo-old rats, 5.09 mM and 0.38 mumol.g-1.2 min-1; 24-mo-old rats, 3.20 mM and 0.25 mumol.g-1.2 min-1. Values for 12-mo-old rats fell in between the other two age groups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
254
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
G631-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Effect of aging on intestinal absorption of aromatic amino acids in vitro in the rat.
pubmed:affiliation
Department of Medicine, University of Arkansas for Medical Sciences, Little Rock 72205.
pubmed:publicationType
Journal Article, In Vitro