Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-5-5
pubmed:abstractText
Proteoglycans are high molecular weight glycoproteins found in connective tissue. They imbibe water into intervertebral disc and apophyseal joint articular cartilage, endowing the tissues with elasticity and compressibility. A decrease in total tissue content of proteoglycans appears to predispose intervertebral disc to degeneration. The earliest tissue changes associated with the onset of spondylosis occur at the molecular level and may include alterations in proteoglycan structure and content. A number of models have been suggested to describe the relationship between changes in proteoglycan composition and degenerative changes in cartilage and intervertebral disc.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0161-4754
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
36-40
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Proteoglycans and degenerative spondylosis.
pubmed:affiliation
Department of Pathology, Faculty of Medicine, Acute Care Hospital, University of British Columbia, Vancouver, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't