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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-5-6
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pubmed:abstractText |
Superfusion of guinea pig hippocampal brain slices with a glucose-free solution induced a membrane hyperpolarization and an increase in input conductance of neurons in the CA3 region. Under voltage clamp, glucose depletion induced an outward current with a reversal potential near the K+ equilibrium potential. The action of glucose depletion was different from the effect of ouabain, indicating that low-glucose-induced changes in the membrane conductance are primarily due to alterations in cell metabolism rather than due only to an inhibition of the Na+/K+ pump.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0014-4886
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
100
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
248-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3350094-Animals,
pubmed-meshheading:3350094-Electric Conductivity,
pubmed-meshheading:3350094-Glucose,
pubmed-meshheading:3350094-Guinea Pigs,
pubmed-meshheading:3350094-Hippocampus,
pubmed-meshheading:3350094-Membrane Potentials,
pubmed-meshheading:3350094-Neurons,
pubmed-meshheading:3350094-Potassium
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pubmed:year |
1988
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pubmed:articleTitle |
Glucose depletion hyperpolarizes guinea pig hippocampal neurons by an increase in potassium conductance.
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pubmed:affiliation |
Department of Physiology, University of Munich, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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