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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-2-9
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pubmed:abstractText |
A seven-year-old boy ingested 3,000 mg (125 mg/kg) of isoniazid. Initial blood levels of isoniazid were 250 micrograms/mL approximately six hours after ingestion. Despite IV treatment in the emergency department with 3,000 mg pyridoxine and a repeat of the same antidote one hour later in the intensive care unit, the high isoniazid blood levels and persistent metabolic acidosis and coma prompted a decision to increase drug clearance by hemodialysis. Clearance data confirmed the effectiveness of hemodialysis in removing the poison, and the clinical response was dramatic.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0196-0644
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
73-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3337420-Acidosis,
pubmed-meshheading:3337420-Blood Gas Analysis,
pubmed-meshheading:3337420-Child,
pubmed-meshheading:3337420-Coma,
pubmed-meshheading:3337420-Emergencies,
pubmed-meshheading:3337420-Humans,
pubmed-meshheading:3337420-Isoniazid,
pubmed-meshheading:3337420-Male,
pubmed-meshheading:3337420-Oliguria,
pubmed-meshheading:3337420-Renal Dialysis,
pubmed-meshheading:3337420-Seizures
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pubmed:year |
1988
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pubmed:articleTitle |
Treatment of a potentially lethal dose isoniazid ingestion.
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pubmed:affiliation |
Pediatric Unit, Cleveland Clinic Foundation, Ohio 44106.
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pubmed:publicationType |
Journal Article,
Case Reports
|