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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1 Pt 1
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pubmed:dateCreated |
1988-1-28
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pubmed:abstractText |
The authors reviewed magnetic resonance (MR) images of 474 consecutive patients referred for lumbar spine MR imaging. Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%). In all cases there was evidence of associated degenerative disk disease at the level of involvement. Histopathologic sections in three cases of type 1 change demonstrated disruption and fissuring of the end plates and vascularized fibrous tissue, while in three cases of type 2 change they demonstrated yellow marrow replacement. In addition, 16 patients with end-plate changes documented with MR were studied longitudinally. Type 1 changes in five of six patients converted to a type 2 pattern in 14 months to 3 years. Type 2 changes in ten patients remained stable over a 2-3-year period. These signal intensity changes appear to reflect a spectrum of vertebral body marrow changes associated with degenerative disk disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0033-8419
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3336678-Adult,
pubmed-meshheading:3336678-Aged,
pubmed-meshheading:3336678-Aged, 80 and over,
pubmed-meshheading:3336678-Bone Marrow,
pubmed-meshheading:3336678-Female,
pubmed-meshheading:3336678-Humans,
pubmed-meshheading:3336678-Intervertebral Disc,
pubmed-meshheading:3336678-Longitudinal Studies,
pubmed-meshheading:3336678-Lumbar Vertebrae,
pubmed-meshheading:3336678-Magnetic Resonance Imaging,
pubmed-meshheading:3336678-Male,
pubmed-meshheading:3336678-Middle Aged,
pubmed-meshheading:3336678-Retrospective Studies,
pubmed-meshheading:3336678-Spinal Diseases
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pubmed:year |
1988
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pubmed:articleTitle |
Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging.
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pubmed:affiliation |
Department of Radiology, University Hospitals of Cleveland, OH 44106.
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pubmed:publicationType |
Journal Article
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