|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1988-4-18
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|
pubmed:abstractText |
The effects of loop diuretics on 36Cl- uptake was tested in isolated beta-cell-rich pancreatic islets. Bumetanide reduced the 36Cl- influx and the levorotatory form of ozolinone reduced both the influx and equilibrium content of 36Cl- in the islets, whereas the dextrorotatory form was largely inactive. The data suggest that the beta-cells are equipped with a loop diuretic-sensitive system for 36Cl- uptake and that this system is confined to a sterically well-defined structure.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0014-2999
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
144
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
389-92
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|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:3326748-Animals,
pubmed-meshheading:3326748-Biological Transport, Active,
pubmed-meshheading:3326748-Bumetanide,
pubmed-meshheading:3326748-Chlorides,
pubmed-meshheading:3326748-Diuretics,
pubmed-meshheading:3326748-Islets of Langerhans,
pubmed-meshheading:3326748-Mice,
pubmed-meshheading:3326748-Mice, Obese,
pubmed-meshheading:3326748-Thiazoles
|
|
pubmed:year |
1987
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|
pubmed:articleTitle |
Stereoselective inhibition of chloride transport by loop diuretics in pancreatic beta-cells.
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|
pubmed:affiliation |
Department of Histology and Cell Biology, University of Umeå, Sweden.
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|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
